primary human islets Search Results


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Prodo Labs human tissue and primary islets
Human Tissue And Primary Islets, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs primary human islets
Primary Human Islets, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sana Biotechnology Inc human hypoimmune primary pancreatic islets
Human Hypoimmune Primary Pancreatic Islets, supplied by Sana Biotechnology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs primary human islet depleted pancreatic acinar cells
Primary Human Islet Depleted Pancreatic Acinar Cells, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs primary human islets from seven normal and five t2d donors (appendix table )
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Primary Human Islets From Seven Normal And Five T2d Donors (Appendix Table ), supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs 2000 islet equivalent of primary human islets, acinar cells, and media for islet culture
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
2000 Islet Equivalent Of Primary Human Islets, Acinar Cells, And Media For Islet Culture, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs primary human islets from adult donors without diabetes
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Primary Human Islets From Adult Donors Without Diabetes, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs human primary islets hp-19226-01
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Human Primary Islets Hp 19226 01, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Prodo Labs biological sample (homo sapiens) primary human pancreatic islets
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Biological Sample (Homo Sapiens) Primary Human Pancreatic Islets, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Primary Cell Co Ltd human islet cdna
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Human Islet Cdna, supplied by Primary Cell Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Insphero Inc primary human islet model
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Primary Human Islet Model, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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BioChain Institute primary human islets
A, B (A) Islet insulin content and (B) islet apoptosis of normal or <t>T2D</t> human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.
Primary Human Islets, supplied by BioChain Institute, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


A, B (A) Islet insulin content and (B) islet apoptosis of normal or T2D human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.

Journal: EMBO Molecular Medicine

Article Title: Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy

doi: 10.15252/emmm.202317928

Figure Lengend Snippet: A, B (A) Islet insulin content and (B) islet apoptosis of normal or T2D human islets with AAV transduction ( n = 8). C, D Representative immunostaining and quantification showing (C) insulin/Ki67 and (D) insulin/TUNEL signals in normal or T2D human islets with AAV transduction ( n = 5–6). Scale bar = 20 μm. E Protein expression of insulin and incretin signaling components in normal or T2D human islets with AAV transduction ( n = 4). F Phosphorylated and total Akt in human islets after 15‐min insulin (100 nM) stimulation ( n = 4). G, H Phosphorylated and total CREB in human islets after 15‐min (G) Exendin‐4 (10 nM) or (H) GIP (10 nM) stimulation ( n = 4). Data information: Each n represents an independent biological replicate (A–H). One‐way ANOVA (A–D). One‐way ANOVA and Kruskal–Wallis test (E). (F–H) Two‐way ANOVA. Data are means ± SEM. ns, nonsignificant. Source data are available online for this figure.

Article Snippet: Primary human islets from seven normal and five T2D donors (Appendix Table ) were obtained from Prodo Laboratories, Inc. (Aliso Viejo, CA, USA).

Techniques: Transduction, Immunostaining, TUNEL Assay, Expressing

A–C (A) Fasting blood glucose, (B) glucose tolerance, and (C) glucose profiles calculated as AUC of control or STZ‐treated mice transplanted with normal or T2D human islets ( n = 7–8). D Serum human insulin ( n = 7–8). E Representative immunostaining showing insulin/glucagon signal and ELISA measurement of human insulin content in human islet grafts ( n = 4–5). Scale bar = 100 μm. F Representative immunostaining and quantification showing insulin/TUNEL signal in human islet grafts ( n = 5). Scale bar = 100 μm. Data information: Each n represents the measurement of a sample from distinct mice (A–F). One‐way ANOVA (A–F). Data are means ± SEM. AUC, area under the curve; ns, nonsignificant. Source data are available online for this figure.

Journal: EMBO Molecular Medicine

Article Title: Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy

doi: 10.15252/emmm.202317928

Figure Lengend Snippet: A–C (A) Fasting blood glucose, (B) glucose tolerance, and (C) glucose profiles calculated as AUC of control or STZ‐treated mice transplanted with normal or T2D human islets ( n = 7–8). D Serum human insulin ( n = 7–8). E Representative immunostaining showing insulin/glucagon signal and ELISA measurement of human insulin content in human islet grafts ( n = 4–5). Scale bar = 100 μm. F Representative immunostaining and quantification showing insulin/TUNEL signal in human islet grafts ( n = 5). Scale bar = 100 μm. Data information: Each n represents the measurement of a sample from distinct mice (A–F). One‐way ANOVA (A–F). Data are means ± SEM. AUC, area under the curve; ns, nonsignificant. Source data are available online for this figure.

Article Snippet: Primary human islets from seven normal and five T2D donors (Appendix Table ) were obtained from Prodo Laboratories, Inc. (Aliso Viejo, CA, USA).

Techniques: Immunostaining, Enzyme-linked Immunosorbent Assay, TUNEL Assay